In 1929, Suzanne de Dietrich was appointed vice-president to the Universal Federation of Christian Students, the spearhead of the then burgeoning ecumenical movement after WWI. She also initiated the first meeting of catholic, protestant and orthodox theologians in 1932.
From then on she presided over numerous multi-confessional bible study groups in France.
In 1929 she was appointed vice-president to the Universal Federation of Christian Students in charge of ecumenical and liturgical matters, and kept her position until 1946.
In 1937 she took part in the first world youth lecture mainly focused on bible study.
She was a member of the consulting committee for the creation of a "method for bible studies" later known as biblical Renewal.
In September 1939 along with Madeleine Barot (1909-1995) she took part in the foundation of the CIMADE (Inter-movement committee along with evacuees) required by the tragic human problems refuges and evacuees were confronted with.
In 1941 she was one of the 16 pastors and lay people - among which 3 women - who wrote the declaration called Thèses de Pomeyrol (Pomeyrol Theses), advocating the resistance of the French Reformed Church to Nazism.
During the war she stayed in Geneva and supported Christian Students' Associations, wrote about their history, and also her most famous book entitled Le Dessein de Dieu (God's Will) - a true account of a biblical itinerary for all believers, and very often used in catholic seminars. It was published in 1945 and translated into 13 languages.